CHOLINERGIC DRUGS


CHOLINERGIC DRUGS



          These are the drugs which produce actions same as acetylcholine, either by directly acting with cholinergic receptors or by increasing availability of Ach at the sites. They are also called as cholinomimetics or parasympathomimetics


          There are two types of Cholinergic drugs they are cholinergic agonists and anticholinesterases


1. CHOLINERGIC AGONISTS


   a) Choline esters:  

                Acetylcholine     

                Methacholine   

                Carbachol        

                Bethanechol


   b)  Alkaloids:

                Muscarine

                Pilocarpine 

                Arecoline


2. ANTICHOLINESTERASES


    a) Reversible


           Carbamates:  

                Physostigmine (Eserine)

                Neostigmine

                Pyridostigmine 

                Rivastigmine

                Edrophonium   

                Donepezil      

                Galantamine 


            Acridine: 

                Tacrine


    b) Irreversible

              

            Carbamates:

                Carbaryl

                Propoxur


            Organophosphates:

                Dyflos (DFP)

                Echothiophate

                Malathione

                Diazinon

                Tabun

                Sarin

                Soman

                Isofluorophate