ANTIDIABETIC DRUGS

(HYPOGLYCAEMIC DRUGS)


INSULIN
    a. Rapid Acting
                Insulin lispro
                Insulin aspart
                Insulin glulisine

    b. Short Acting
                Regular (soluble) Insulin
                Prompt Insulin Zinc Suspension (amorphous) or Semilente

    c. Intermediate Acting
                Insulin Zinc Suspension or Lente
                Neutral Protamine Hagedorn (NPH) or Isophane Insulin

    d. Long Acting
                Extended Insulin Zinc Suspension (crystalline) or Ultralente
                Protamine Zinc Insulin (PZI)
                Insulin glargine

ORAL HYPOGLYCAEMIC DRUGS
                                                   
1. SULFONYLUREAS
     a. First generation   
                Tolbutamide   
                Chlorpropamide       

     b. Second generation
                Glibenclamide (Glyburide)
                Glipizide
                Gliclazide
                Glimepiride

2. BIGUANIDE
                Metformin

3. MEGLITINIDE/PHENYLALANINE ANALOGUES
                Repaglinide    
                Nateglinide

4. THIAZOLIDINEDIONES
                Rosiglitazone
                Pioglitazone

5. α - GLUCOSIDASE INHIBITORS
                Acarbose    
                Miglitol

6. DIPEPTIDYL PEPTIDASE-4 (DPP-4) INHIBITOR
                Sitagliptin
                Vildagliptin

7. AMYLIN ANALOGUE
                Pramlintide

8. DOPAMINE D2 AGONIST
                Bromocriptine

9. SOD-GLUCOSE COTRANSPORT-2 INHIBITOR
                Dapagliflozin