RUDRA'S PHARMACOLOGY

DIURETICS

1. High efficacy diuretics (Inhibitors of Na+-K+-2Cl¯ cotransport)

    a. Sulphamoyl derivatives:

                Furosemide

                Bumetanide

                Torasemide

    b. Phenoxyacetic acid derivative:

                Ethacrynic acid

2. Medium efficacy diuretics (Inhibitors of Na+-Cl¯ symport)

    a. Benzothiadiazines (thiazides):

                Hydrochlorothiazide

                Benzthiazide

                Hydroflumethiazide

                Clopamide

    b. Thiazide like (related heterocyclics):

                Chlorthalidone

                Metolazone

                Xipamide

                Indapamide

3. Weak or adjunctive diuretics

    a. Carbonic anhydrase inhibitors:

                Acetazolamide

    b. Potassium sparing diuretics:

        Aldosterone antagonist:

                Spironolactone

                Eplerenone

        Inhibitors of renal epithelial Na+ channel:

                Triamterene

                Amiloride

    c. Osmotic diuretics:

                Mannitol

                Isosorbide

                Glycerol

    d. Xanthines: 

                Theophylline