RUDRA'S PHARMACOLOGY

DRUGS FOR GASTROESOPHAGEAL REFLUX DISEASE (GERD)

1. Inhibitors/neutralizers of gastric acid secretion

    a. Proton pump inhibitors (PPIs):

                Omeprazole

                Pantoprazole and others

    b. H₂  blockers:

                Ranitidine

                Famotidine

    c. Antacids:

                Magnesium hydroxide

                Aluminium hydroxide

2. Barrier agent

                Sodium alginate

3. Prokinetic drugs: (Enhance LES tone and promote gastric emptying)

                Cisapride

                Mosapride

                Metoclopramide

LES: Lower Esophagial Sphincter